News

BenevolentAI named as one of Fierce Medtech’s Fierce 15 of 2020

BenevolentAI has been selected as one of the most promising private companies in the industry by Fierce Medtech in its Fierce 15 2020 list.

The annual Fierce 15 competition whittles down nominations from around the globe to recognise fifteen medical technology companies leading in innovation and creativity. This accolade is demonstrative of a year of embracing new milestones at Benevolent, and a testament to our cutting-edge technology and powerful collaborations. 

As Conor Hale, Associate Editor of Fierce Medtech commented: “Each member of this year’s class of Fierce 15 stands out in a different way, but they all overcame a year of unforgettable obstacles, making each of their successes that much more significant.”

Despite the disruption caused by the global pandemic and accompanying lockdowns, 2020 saw us achieve impactful results. Our COVID-19 research, which began in January 2020, led to us identifying baricitinib as a potential treatment across one weekend. Just nine  months later, baricitinib became one of the few coronavirus treatments approved by the FDA for emergency use. 

In parallel, we continued to push ahead with our AstraZeneca collaboration. In April 2020, we delivered the first output of hypotheses for CKD; and more recently, AstraZeneca selected the first AI-generated CKD target for their portfolio after it was biologically validated via their rigorous experimental testing. Our  data-driven approach integrated AstraZeneca’s disease experts alongside our data scientists, bioinformaticians and machine learning engineers. This cross-functional connection continues to yield new ideas and leads us to generating  novel, higher quality targets whilst reducing the time traditionally taken  to discover a potential drug candidate. 

Simultaneously, we continued to deepen and strengthen our internal pipeline of drug programmes. In February 2021 we dosed the first patient in the randomised clinical trial of BEN-2293, a molecule we designed and developed to treat atopic dermatitis. We hope this treatment will address the inflammation and itch that makes the disease so difficult to endure. 

The drug discovery industry still faces significant challenges. It is expensive and high risk, with long R&D cycles, which cost today’s patients. There has never been a more critical time to play a part in changing this, and by fusing human and machine intelligence we believe we can help to shorten this complex process and create  treatments which are more effective for patients.

Is our goal an ambitious one? Absolutely. But we believe we have only just started to see the impact of our technology and approach and are eager to see what achievements and progress lie ahead. We are delighted to be recognised amongst fellow tech pioneers by Fierce Medtech at this stage of our journey.


More Posts

You Might Also Like

Blog
AI in Drug Discovery
This blog seeks to demystify the application of artificial intelligence (AI) and machine learning (ML) in drug discovery by exploring some of the challenges, opportunities and progress that has been achieved in the field so far.
Jul 13, 2021
News
BenevolentAI announces the appointment of biopharma luminary Dr François Nader as Chairman
Dr Nader joins BenevolentAI as it embarks on ambitious growth plans to scale its AI platform, partnerships and drug portfolio.
Jul 9, 2021
Blog
Product design in AI-drug discovery: how to design products for and with scientific users
User interfaces can help drug discovery scientists to leverage insights from AI algorithms. Yet, designing products to enable scientific discovery is complex. Our product designer, Róża explores the key steps in her design process.
Jul 6, 2021
News
Baricitinib, first identified by BenevolentAI as a COVID-19 treatment, is granted emergency use in India in response to its escalating crisis
Baricitinib - first identified by BenevolentAI as a potential COVID-19 treatment - is accelerated for use in hospitalised patients in India following a continued surge in cases and fatalities.
May 5, 2021
Video
A New Era in Target Discovery: Collaborating with AstraZeneca on CKD and IPF
Finding the right target underpins the success of the entire drug discovery process. Learn how BenevolentAI’s collaboration with AstraZeneca is making a difference in CKD and IPF.
Apr 23, 2021
News
Data from Eli Lilly’s COV-BARRIER trial shows baricitinib reduced deaths in hospitalised COVID-19 patients by 38%
The latest data published in Eli Lilly’s Phase 3 randomised, double-blind, placebo-controlled study (COV-BARRIER) shows the largest clinical effect reported to date for a reduction in mortality in the COVID-19 patient population
Apr 8, 2021