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Drug Discovery

Principal Molecular Pharmacologist Scientist

With over 35 nationalities and a range of backgrounds represented in our Benevolent team, we aim to build an inclusive environment where our people can bring their authentic selves to work, be respected for who they are and the exceptional work they do. We welcome and actively encourage applications from all sections of society and are committed to offering equal employment opportunities regardless of sex, race, religion or belief, ethnic or national origin, marital, domestic or civil partnership status, sexual orientation, gender identity, parental status, disability, age, citizenship, or any other basis. We see our diversity as an asset as we tackle challenging problems that bridge the gap between drug discovery and technology.


The Role

We are looking for a number of innovative and highly creative drug discovery scientists with a background in molecular pharmacology and/or molecular and cellular biology, particularly in the context of pathological mechanisms underlying human diseases.

You will make significant contributions to our technology-enabled drug discovery programmes by generating novel therapeutic target hypotheses and delivering robust preclinical target validation data packages. You will apply your deep understanding of biological processes and drug discovery to rapidly move projects through preclinical research and development.

Based at our London office, you will work closely with experts in drug discovery, artificial intelligence, informatics, patient stratification, clinical translation and commercialisation. This is a non-lab based position.

Primary Responsibilities

  • With a strong molecular and cell biology background and an understanding of mechanisms underlying human disease, you will contribute to the generation and prioritisation of novel therapeutic hypotheses across a range of disease areas.
  • You will be responsible for providing leadership to define and implement experimental plans to validate these therapeutic hypotheses using cell-based disease-relevant models.
  • You will critically analyse and interpret data, define realistic timelines for studies, and meet delivery deadlines within a fast-paced and collaborative environment.
  • You will contribute to the identification and assessment of business development opportunities as well as fostering external collaborative relationships with academic leaders and contract research scientists.

Additional Responsibilities

  • Familiarity with working within small or large molecule drug discovery programs as a biology representative with a basic understanding of associated disciplines, e.g. DMPK, toxicity/safety assessment and medicinal chemistry would be desirable

We are looking for someone with

  • BSc / MSc / PhD in biological sciences with 3+ years of experience in the application of molecular pharmacology principles to the drug discovery arena or a closely related discipline.
  • Evidence of creative thinking and problem solving, confidently applying novel strategies to move projects to important decision points quickly and efficiently.
  • Track record of significant contributions to shaping project strategies and successfully delivering results to answer key scientific questions, ideally within the drug discovery industry.
  • Experience in one or more areas of human disease or mechanistic pathways associated with disease, such as neurodegeneration, immunology, fibrosis, diseases of aging or oncology.
  • Track record of prioritising and initiating new projects and areas of research, integrating data and expertise from multiple sources, with changing priorities and deadlines.
  • Experience of working with Contract Research providers: CRO selection, design & agreement of work plans and analysis of data packages would be an advantage
  • Experience of successfully working in multi-disciplinary teams, ideally in a drug discovery & development environment, with excellent communication skills and the ability to forge productive relationships and collaborations both internally and externally.

We share a passion for being part of a mission that matters, and we are always looking for curious and collaborative people who share our values and want to be part of our journey.  If that sounds like a fit for you, hit the apply button and join us.

About us

BenevolentAI (AMS: BAI) is a leading, clinical-stage AI-enabled drug discovery and development company listed on the Euronext Amsterdam stock exchange. Through the combined capabilities of its AI platform, scientific expertise, and wet-lab facilities, BenevolentAI is well-positioned to deliver novel drug candidates with a higher probability of clinical success than those developed using traditional methods. The Benevolent Platform™ powers a growing in-house pipeline of 13 named drug programmes and over 10 exploratory programmes, and it maintains successful collaborations with AstraZeneca, as well as leading research and charitable institutions. BenevolentAI is headquartered in London, with a research facility in Cambridge (UK) and a further office in New York.

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