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Drug Discovery

Drug Discovery Scientist - InVitro Biology

With over 35 nationalities and a range of backgrounds represented in our Benevolent team, we aim to build an inclusive environment where our people can bring their authentic selves to work, be respected for who they are and the exceptional work they do. We welcome and actively encourage applications from all sections of society and are committed to offering equal employment opportunities regardless of sex, race, religion or belief, ethnic or national origin, marital, domestic or civil partnership status, sexual orientation, gender identity, parental status, disability, age, citizenship, or any other basis. We see our diversity as an asset as we tackle challenging problems that bridge the gap between drug discovery and technology.


The Role

We are looking for a number of enthusiastic and motivated drug discovery scientists to join our In Vitro Biology team focusing on novel target identification, assay development and screening. You will contribute to our technology-enabled drug discovery programmes, from hit identification through to pre-clinical. As a central member of a dynamic, multi-disciplinary team of scientists passionate about reinventing the way new medicines are developed, you will bring your understanding of in vitro biological technologies and drug discovery to progress projects into clinical evaluation.

Primary Responsibilities

  • Identify and establish relevant in vitro assays for target identification and validation projects. Perform screens with small molecules or genetic approaches (siRNA, shRNA, CRISPR).
  • Develop and optimise relevant biochemical or cell-based assays for medium to high throughput screening of novel therapeutic compounds to support pipeline projects.
  • Maintain cell cultures including cell lines, primary cells and/or iPSCs.
  • Generate detailed SOPs and follow assay protocols.
  • Critically analyse and interpret data, define realistic timelines for studies and meet delivery deadlines to execute high impact studies.

We are looking for someone with

  • BSc, MSc or equivalent in biological sciences or a closely related discipline. Industry research experience is preferred but not required.
  • Ability to work independently.
  • Attention to detail.

Nice to haves - we have several openings and experience with one or more of the below would be desired but not required.

  • Experience with cell lysis, cellular fractionation, co-immunoprecipitation and Western blotting.
  • Experience with RNA extraction, qPCR, RNAseq workflows and data analysis.
  • Experience with in vitro plate-based biochemical assays and technologies (absorbance, fluorescence, TR-FRET, luminescence, etc).
  • Experience with a range of cellular assays and technologies (ELISA, MSD, reporter gene, high content & live-cell imaging, flow cytometry).
  • Experience working in cell culture with immortalised cell lines, primary cells, iPSCs, primary tissue and complex cultures (co-cultures or 3D cultures).
  • Familiarity with electronic lab notebooks.

We share a passion for being part of a mission that matters, and we are always looking for curious and collaborative people who share our values and want to be part of our journey.  If that sounds like a fit for you, hit the apply button and join us.

About us

BenevolentAI (AMS: BAI) is a leading, clinical-stage AI-enabled drug discovery and development company listed on the Euronext Amsterdam stock exchange. Through the combined capabilities of its AI platform, scientific expertise, and wet-lab facilities, BenevolentAI is well-positioned to deliver novel drug candidates with a higher probability of clinical success than those developed using traditional methods. The Benevolent Platform™ powers a growing in-house pipeline of 13 named drug programmes and over 10 exploratory programmes, and it maintains successful collaborations with AstraZeneca, as well as leading research and charitable institutions. BenevolentAI is headquartered in London, with a research facility in Cambridge (UK) and a further office in New York.

Want to do a little more research before you apply?

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