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InVitro
London

Drug Discovery Outsourcing Scientist

With over 35 nationalities and a range of backgrounds represented in our Benevolent team, we aim to build an inclusive environment where our people can bring their authentic selves to work, be respected for who they are and the exceptional work they do. We welcome and actively encourage applications from all sections of society and are committed to offering equal employment opportunities regardless of sex, race, religion or belief, ethnic or national origin, marital, domestic or civil partnership status, sexual orientation, gender identity, parental status, disability, age, citizenship, or any other basis. We see our diversity as an asset as we tackle challenging problems that bridge the gap between drug discovery and technology.

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The Role

The Discovery Enabling Team (DET) is a cross-discipline team which supports the research activities of BenevolentAI’s scientists, research informaticians, machine learning and AI technologists. We are looking for a talented Discovery Scientist to join this team to manage and support selectivity and safety screening across our Drug Discovery portfolio. You will be responsible for streamlining data-capture across our AI-driven pipeline throughout the drug discovery process to Candidate Development. Working closely with our Drug Discovery Scientists, you will directly advise and share your knowledge of outsourced-assays, their set up and data capture. You will work with project teams to define study requirements, help researchers set up pilot assays as well as running, QC-qualifying, and interpreting established screens. You will manage these datasets in Dotmatics ELNs and ensure that quality data is fed back to the teams in a timely fashion.

Primary Responsibilities

  • DET outsourcing activities, for example Selectivity & safety pharmacology screens, primary pharmacology screens.
  • Manage outsourcing operations; including data back and circulation, compound ordering and shipping logistics, quotation requests, CRO contract relationships, and budget management,
  • QC data, upload and record outcomes in Electronic Laboratory Notebooks (ELNs), for on time sharing of key results with relevant project teams
  • Serve as a key DET-point of contact to internal Project Teams, the Safety Team, Project Management, Finance, and CROs
  • Continuously improve DET’s compound-to-data workflows, Dotmatics data capture and data presentation across Drug Discovery
  • Coordinate with key stakeholders to ensure all study requirements are met; including Target Identification program leads, drug discovery core teams, safety pharmacology, Project Management, Finance and external CROs
  • Participate in the organisation and logistics of business and collaboration meetings
  • Ensure assay requests and data strategies are developed and implemented within the expected timelines, across multiple Project and Target Identification teams
  • Keep up to date with technical developments in key fields, eg target and selectivity screening, safety pharmacology

We are looking for someone with

  • Experience of drug discovery from a small or large Pharma, Biotech or CRO
  • Good knowledge of drug discovery as it pertains to primary pharmacology, selectivity and safety pharmacology
  • Outsourcing experience at any stage of the drug discovery pipeline, from early target identification to candidate nomination
  • Experience of data interpretation and QC e.g. troubleshooting and understanding curve fits
  • Proven ability to multitask; organise, coordinate and interpret multiple studies across different projects at the same time while effectively prioritising work and responding to changing situations
  • A proactive problem solver and clear communicator, who can suggest innovative solutions to improve workflows and data availability
  • A positive attitude and collaborative approach, with the ability to work effectively across broad-discipline internal teams and external-vendors to develop, integrate, ‘prove’ and support workflows
  • A team player who is able to learn new technology and enjoys assisting others
Nice to haves:
  • Working knowledge of the best CROs for performing in vitro studies
  • Working knowledge of internal and/or commercial data-management tools; including but not limited to Dotmatics, Excel-macros/XLfit, Prism, IDBS-ActivityBase and Chem/Bio ELNs
  • Familiarity with current regulatory guidelines relating to the drug development process
  • Experience and understanding of the challenges in handling large datasets

We share a passion for being part of a mission that matters, and we are always looking for curious and collaborative people who share our values and want to be part of our journey.  If that sounds like a fit for you, hit the apply button and join us.

About us

BenevolentAI (AMS: BAI) is a leading, clinical-stage AI-enabled drug discovery company listed on the Euronext Amsterdam stock exchange. Through the combined capabilities of its AI platform, scientific expertise, and wet-lab facilities, BenevolentAI is well-positioned to deliver novel drug candidates with a higher probability of clinical success than those developed using traditional methods. BenevolentAI has a consistently proven track record of scientifically validated discoveries. The BenevolentAI Platform™ powers a growing in-house pipeline of over 20 disease programmes, spanning from target discovery to clinical studies, and it maintains successful collaborations with AstraZeneca, as well as leading research and charitable institutions. BenevolentAI is headquartered in London, with a research facility in Cambridge (UK) and a further office in New York.

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