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InVitro
London

Biology Project Leader

With over 35 nationalities and a range of backgrounds represented in our Benevolent team, we aim to build an inclusive environment where our people can bring their authentic selves to work, be respected for who they are and the exceptional work they do. We welcome and actively encourage applications from all sections of society and are committed to offering equal employment opportunities regardless of sex, race, religion or belief, ethnic or national origin, marital, domestic or civil partnership status, sexual orientation, gender identity, parental status, disability, age, citizenship, or any other basis. We see our diversity as an asset as we tackle challenging problems that bridge the gap between drug discovery and technology.

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The Role

BenevolentAI has two opportunities for biological scientists with experience in leading drug discovery programmes. These individuals, depending on experience, will provide either overall or biology leadership of technology-enabled small molecule drug discovery programmes optimising lead compounds into candidates for preclinical development.

As a central member of a dynamic, multi-disciplinary team of scientists passionate about the potential of technology-assisted drug discovery and development, you will bring your proven resilient leadership and ability to make pragmatic data-driven decisions to advance our ever-expanding portfolio of small molecule programs. Based at our London offices off Tottenham Court Road, you will work closely with a diverse range of experts in biological sciences, chemical sciences, clinical, commercialisation, artificial intelligence (AI), deep/machine learning (ML) and informatics teams to enrich the BenevolentAI portfolio.

Primary Responsibilities

  • Provide biology leadership for small molecule drug discovery programs from hit identification through to preclinical development candidate nomination
  • Devise, lead and implement clear concise short, medium and long term strategies to identify small molecule drugs
  • Based on one’s drug discovery experience and input from diverse discipline experts, make data driven decisions to advance programmes through stage gates within timelines and budgets
  • Responsible/accountable for overall project biology, regularly reporting progress and issues with clear strategic recommendations to the project leader, the project team and senior leadership when required
  • Coordinate with project managers and functions to ensure the appropriate resource and experience are supporting the project team at the required time and that assigned resources are effectively utilised

We are looking for someone with

  • BSc / MSc / PhD in biological sciences with 3 - 8 years of industry research experience, preferably consisting of at least 1 - 4 years providing either domain area, specifically biology, or overall leadership for small molecule drug discovery programmes
  • Proven ability to provide biology domain area leadership for small molecule drug discovery programmes through stage gates to at least lead optimisation but preferably to Candidate nomination
  • Experience successfully leading/working in multi-disciplinary drug discovery & development teams, with excellent communication skills and the ability to forge productive relationships and collaborations both internally and externally
  • Sufficient depth of knowledge of medicinal chemistry, DMPK, in-vitro/in-vivo biology and safety pharmacology/toxicology to devise/adapt screen sequences and to make decisions based on screen sequence data and advice from project team experts
  • Ability to work under pressure, manage different projects and deliver to defined timelines
  • Experience in one or more areas of human disease or mechanistic pathways associated with disease, such as neurodegeneration, inflammation, fibrosis, metabolic diseases or oncology, is desirable
  • Evidence of creative thinking and problem solving, confidently applying novel strategies to move projects to important decision points quickly and efficiently
  • Excellent oral and written communication skills e.g. can tailor the complexity of communications as and when required, whilst maintaining clarity of communication
Nice to haves:
  • Familiarity with discovering other therapeutic modalities, e.g. large molecules, is desirable but not essential
  • Familiarity with target identification and validation strategies across a range of diseases is desirable
  • Familiarity with preclinical development of small molecules is desirable

We share a passion for being part of a mission that matters, and we are always looking for curious and collaborative people who share our values and want to be part of our journey.  If that sounds like a fit for you, hit the apply button and join us.

About us

BenevolentAI (AMS: BAI) is a leading, clinical-stage AI-enabled drug discovery and development company listed on the Euronext Amsterdam stock exchange. Through the combined capabilities of its AI platform, scientific expertise, and wet-lab facilities, BenevolentAI is well-positioned to deliver novel drug candidates with a higher probability of clinical success than those developed using traditional methods. The Benevolent Platform™ powers a growing in-house pipeline of 13 named drug programmes and over 10 exploratory programmes, and it maintains successful collaborations with AstraZeneca, as well as leading research and charitable institutions. BenevolentAI is headquartered in London, with a research facility in Cambridge (UK) and a further office in New York.

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Important Note

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